"Il33" Related Products

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Recombinant Rat Interleukin 33

Cat. No.: Il33-286R
Product Overview: Recombinant rat IL-33 (aa 109-264) was expressed in E. coli, ~16kDa.
Description: IL-33 is a new member of the IL-1 family. It is involved in T helper type 2 response via the activation of its receptor ST2 (IL-1RL1) driving the production of Th2-associated cytokines. The stimulation of ST2 by IL-33 induces the NF-κB and MAPK pathways. The human IL-33 protein is expressed with a prodomain (aa 1-111) which is cleaved by caspase-1 to produce the 18kDa mature protein (112-270).
Source: E. coli.
Purity: ≥95% (SDS-PAGE).
Concentration: 0.1mg/ml after reconstitution.
Formulation: Lyophilized. Contains PBS.
Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution: Reconstitute with 100µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum.
Long Term Storage: -20°C.
Use/Stability: Stable for at least 6 months after receipt when stored at -20°C.
Handling: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Gene Name: Il33 interleukin 33 [ Rattus norvegicus ]
Synonyms: interleukin 33; RGD1311155; Il33; interleukin-33; IL-33
Gene ID: 361749
mRNA Refseq: NM_001014166
Protein Refseq: NP_001014188
UniProt ID: Q66H70
Chromosome Location: 1q52
Pathway: Cytosolic DNA-sensing pathway
Function: cytokine activity; protein binding

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