"NTN1" Related Products


Recombinant Human Netrin 1, FLAG-tagged

Cat. No. : NTN1-2173H
Product Overview : Recombinant Human Netrin 1 (aa 28-604) is produced inHEK 293cell and fused at the N-terminus to a FLAG-tag. MW= 85kDa.
Description : The Netrins (whose name means "one who guides" in Sanskrit) are a family of laminin-related secreted protein. In mice, human and rat, netrin-1, netrin-3/NTL2, netrin-4 and G-netrins have been cloned. Netrin-1 is predominantly expressed by floor plate cells as commissural axons extend toward the ventral midline. Netrin-1 induces axonal outgrowth, axon orientation and neuronal migration in neuronal development. It is chemoattractive for some neurons and chemorepellent for others.
Source : HEK 293.
Concentration : 0.1mg/ml after reconstitution.
Purity : ≥95% (SDS-PAGE).
Formulation : Lyophilized. Contains PBS.
Specificity : Binds to human, mouse and rat receptors UNC5H and DCC.
Reconstitution : Reconstitute with 100µl sterile distilled water. Resuspended protein should be used immediately upon reconstitution to avoid loss in activity due to non-specific binding to the vial. Further dilutions should be made with medium containing 5% fetal calf serum or 0.5% BSA.
Storage And Stability : Stable for at least 6 months after receipt when stored at -20°C. Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Gene Name : NTN1 netrin 1 [ Homo sapiens ]
Synonyms : NTN1; netrin 1; NTN1L; Netrin-1; netrin 1, mouse, homolog of
Gene ID : 9423
mRNA Refseq : NM_004822
Protein Refseq : NP_004813
MIM : 601614
UniProt ID : O95631
Chromosome Location : 17p13-p12
Pathway : Axon guidance
Function : protein binding

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