"PARP3" Related Products


Recombinant Human PARP3, His-tagged

Cat. No.: PARP3-642H
Product Overview: Recombinant Human PARP3 is produced inSf21cells and fused at the N-terminus to a His-tag.
Description: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source: Sf21.
Purity: ≥98% (SDS-PAGE).
Concentration: 1mg/ml.
Formulation: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 50mM imidazole, 0.2% NP-40 and 10% glycerol.
Storage And Stability: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
Gene Name: PARP3 poly (ADP-ribose) polymerase family, member 3 [ Homo sapiens ]
Synonyms: PARP3;poly (ADP-ribose) polymerase family, member 3; EC; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3; ADPRT-3; NAD(+) ADP-ribosyltransferase 3; NAD+ ADP-ribosyltransferase 3; poly [ADP-ribose] polymerase 3; poly(ADP-ribose) synthetase-3; poly[ADP-ribose] synthase 3; poly[ADP-ribose] synthetase 3; IRT1; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3; EC
Gene ID: 10039
mRNA Refseq: NM_001003931
Protein Refseq: NP_001003931
MIM: 607726
UniProt ID: Q9Y6F1
Chromosome Location: 3p21.31-p21.1
Pathway: Base excision repair
Function: NAD+ ADP-ribosyltransferase activity; identical protein binding; transferase activity, transferring glycosyl groups

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