Human ACAT2 Knockdown Cell Lysate

• Cat.No.: ACAT2-020HKCL
• Product Overview: WB-validated ACAT2 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 41 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg ACAT2 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Butanoate metabolism, Fatty acid metabolism, leucine and isoleucine degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: ACAT2 acetyl-CoA acetyltransferase 2 [ Homo sapiens (human) ]
• Official Symbol: ACAT2
• Synonyms: ACAT2; acetyl-CoA acetyltransferase 2; acetyl Coenzyme A acetyltransferase 2, acetyl Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase); acetyl-CoA acetyltransferase, cytosolic; acetoacetyl Coenzyme A thiolase; cytosolic acetoacetyl-CoA thiolase; acetyl-CoA transferase-like protein
• Gene ID: 39
• mRNA Refseq: NM_005891
• Protein Refseq: NP_005882
• MIM: 100678
• UniProt ID: Q9BWD1