Human AK4 Knockdown Cell Lysate

• Cat.No.: AK4-031HKCL
• Product Overview: WB-validated AK4 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 25 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg AK4 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: AK4 adenylate kinase 4 [ Homo sapiens (human) ]
• Official Symbol: AK4
• Synonyms: AK4; adenylate kinase 4; adenylate kinase 3, adenylate kinase 3 like 1, AK3, AK3L1; adenylate kinase isoenzyme 4, mitochondrial; adenylate kinase 3-like 1; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase; AK3; AK3L1; AK3L2; MGC166959
• Gene ID: 205
• mRNA Refseq: NM_001005353
• Protein Refseq: NP_001005353
• MIM: 103030
• UniProt ID: P27144