"IAPP" Related Products


Human Amylin, Amide

Cat.No. : IAPP-001H
Product Overview : CAS No. 122384-88-7
C Terminal: NH2
Disulfide Bridge: Cys2-Cys7
Format Bridge: 2-7
Description : Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.
Source : Synthetic
Species : Human
Molecular Mass : 3903.28 Da
AA Sequence : Sequence: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
Purity : > 95%
Storage : Store at -20 centigrade. Keep container tightly closed. Store in a cool dry place.
Reconstitution : Can be dissolved in DMSO or DMF first and then dilute with water
Gene Name : IAPP
Official Symbol : IAPP islet amyloid polypeptide [ Homo sapiens (human) ]
Synonyms : IAPP; islet amyloid polypeptide; DAP; IAP; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin)
amylin; diabetes-associated peptide; insulinoma amyloid peptide
Gene ID : 3375
mRNA Refseq : NM_000415
Protein Refseq : NP_000406
MIM : 147940
UniProt ID : P10997

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