Human CD99 Knockdown Cell Lysate

• Cat.No.: CD99-098HKCL
• Product Overview: WB-validated CD99 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 19 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CD99 KD HeLa cell lysate
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: CD99 CD99 molecule [ Homo sapiens (human) ]
• Official Symbol: CD99
• Synonyms: CD99; CD99 molecule; antigen identified by monoclonal antibodies 12E7, F21 and O13, CD99 antigen, MIC2; CD99 antigen; E2 antigen; surface antigen MIC2; T-cell surface glycoprotein E2; MIC2 (monoclonal 12E7); antigen identified by monoclonal 12E7, Y homolog; antigen identified by monoclonal antibodies 12E7, F21 and O13; MIC2; HBA71; MIC2X; MIC2Y; MSK5X
• Gene ID: 4267
• mRNA Refseq: NM_001122898
• Protein Refseq: NP_001116370
• MIM: 313470
• UniProt ID: P14209