Human CLP1 Knockdown Cell Lysate

• Cat.No.: CLP1-116HKCL
• Product Overview: WB-validated CLP1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 48 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CLP1 KD HeLa cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: CLP1 cleavage factor polyribonucleotide kinase subunit 1 [ Homo sapiens (human) ]
• Official Symbol: CLP1
• Synonyms: CLP1; cleavage factor polyribonucleotide kinase subunit 1; HEAB; hClp1; polyribonucleotide 5'-hydroxyl-kinase Clp1 ATP/GTP-binding protein cleavage and polyadenylation factor I subunit 1 homolog of yeast CFIA subunit Clp1p polyadenylation factor Clp1 polynucleotide kinase Clp1 pre-mRNA cleavage complex II protein Clp1 EC 2.7.1.78
• Gene ID: 10978
• mRNA Refseq: NM_006831
• Protein Refseq: NP_006822
• MIM: 608757
• UniProt ID: Q92989