Human CTNNA1 Knockdown Cell Lysate

• Cat.No.: CTNNA1-128HKCL
• Product Overview: WB-validated CTNNA Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 100 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CTNNA KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa [ Homo sapiens (human) ]
• Official Symbol: CTNNA1
• Synonyms: CTNNA1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin associated protein), alpha 1 (102kD); catenin alpha-1; CAP102; alpha-catenin; alphaE-catenin; alpha E-catenin; alpha-E-catenin; renal carcinoma antigen NY-REN-13; cadherin-associated protein,102kDa; FLJ36832; FLJ52416
• Gene ID: 1495
• mRNA Refseq: NM_001903
• Protein Refseq: NP_001894
• MIM: 116805
• UniProt ID: P35221