Human EMD Knockdown Cell Lysate

• Cat.No.: EMD-156HKCL
• Product Overview: WB-validated EMD Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 29 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg EMD KD HeLa cell lysate
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: EMD emerin [ Homo sapiens (human) ]
• Official Symbol: EMD
• Synonyms: EMD; emerin; Emery Dreifuss muscular dystrophy; LEM domain containing 5; LEMD5; STA; EDMD
• Gene ID: 2010
• mRNA Refseq: NM_000117
• Protein Refseq: NP_000108
• MIM: 300384
• UniProt ID: P50402