Recombinant Human EMD

• Cat.No.: EMD-28289TH
• Product Overview: Recombinant full length Human Emerin with proprietary tag. Mol Wt 54.01

Specification

• Description: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
• Protein length: 254 amino acids
• Molecular Weight: 54.010kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Skeletal muscle, heart, colon, testis, ovary and pancreas.
• Biological activity: useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Reduced glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 LEM domain.

Gene Information

• Gene Name: EMD emerin [ Homo sapiens ]
• Official Symbol: EMD
• Synonyms: EMD; emerin; Emery Dreifuss muscular dystrophy; LEM domain containing 5; LEMD5; STA
• Gene ID: 2010
• mRNA Refseq: NM_000117
• Protein Refseq: NP_000108
• MIM: 300384
• Uniprot ID: P50402
• Chromosome Location: Xq27.3-q28
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem
• Function: actin binding; beta-tubulin binding; protein binding