Human G6PD Knockdown Cell Lysate

• Cat.No.: G6PD-169HKCL
• Product Overview: WB-validated G6PD Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 59 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg G6PD KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: G6PD glucose-6-phosphate dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: G6PD
• Synonyms: G6PD; glucose-6-phosphate dehydrogenase; glucose-6-phosphate 1-dehydrogenase; G6PD1; glucose-6-phosphate dehydrogenase, G6PD
• Gene ID: 2539
• mRNA Refseq: NM_000402
• Protein Refseq: NP_000393
• MIM: 305900
• UniProt ID: P11413