Human LRP8 Knockdown Cell Lysate

• Cat.No.: LRP8-231HKCL
• Product Overview: WB-validated LRP8 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 106 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg LRP8 KD HeLa cell lysate
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [ Homo sapiens (human) ]
• Official Symbol: LRP8
• Synonyms: LRP8; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; low-density lipoprotein receptor-related protein 8; APOER2; ApoE receptor 2; MCI1; LRP-8; HSZ75190
• Gene ID: 7804
• mRNA Refseq: NM_001018054
• Protein Refseq: NP_001018064
• MIM: 602600
• UniProt ID: Q14114