Human NSDHL Knockdown Cell Lysate

• Cat.No.: NSDHL-381HKCL
• Product Overview: WB-validated NSDHL Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 42 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg NSDHL KD HeLa cell lysate
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Steroid biosynthesis
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: NSDHL NAD(P) dependent steroid dehydrogenase-like [ Homo sapiens (human) ]
• Official Symbol: NSDHL
• Synonyms: NSDHL; NAD(P) dependent steroid dehydrogenase-like; sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; H105e3; SDR31E1; short chain dehydrogenase/reductase family 31E; member 1; XAP104; protein H105e3; short chain dehydrogenase/reductase family 31E, member 1; H105E3
• Gene ID: 50814
• mRNA Refseq: NM_001129765
• Protein Refseq: NP_001123237
• MIM: 300275
• UniProt ID: Q15738