Human PRPF4 Knockdown Cell Lysate

• Cat.No.: PRPF4-405HKCL
• Product Overview: WB-validated PRPF4 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 58 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg PRPF4 KD HeLa cell lysate
• Protein Pathways: Spliceosome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) [ Homo sapiens (human) ]
• Official Symbol: PRPF4
• Synonyms: PRPF4; PRP4 pre-mRNA processing factor 4 homolog (yeast); U4/U6 small nuclear ribonucleoprotein Prp4; HPRP4; HPRP4P; PRP4; PRP4/STK/WD splicing factor; Prp4p; PRP4 homolog; WD splicing factor Prp4; U4/U6 snRNP 60 kDa protein
• Gene ID: 9128
• mRNA Refseq: NM_001244926
• Protein Refseq: NP_001231855
• MIM: 607795
• UniProt ID: O43172