Human SUOX Knockdown Cell Lysate

• Cat.No.: SUOX-438HKCL
• Product Overview: WB-validated SUOX Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 60 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg SUOX KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Sulfur metabolism
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: SUOX sulfite oxidase [ Homo sapiens (human) ]
• Official Symbol: SUOX
• Synonyms: SUOX; sulfite oxidase; sulfite oxidase, mitochondrial
• Gene ID: 6821
• mRNA Refseq: NM_000456
• Protein Refseq: NP_000447
• MIM: 606887
• UniProt ID: P51687