| Species : |
Human |
| Source : |
HeLa |
| Tag : |
Non |
| Description : |
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. |
| Form : |
Cell-Tissue Lysis buffer |
| Molecular Mass : |
70 kDa |
| Notes : |
Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins. |
| Storage : |
Store at -20 centigrade for two years. |
| Concentration : |
Lot-specific |
| Shipping : |
Blue Ice |
| Components : |
1 vial of 100 μg WT HeLa cell lysate
1 vial of 100 μg TP73 KD HeLa cell lysate |
| Protein Families : |
Druggable Genome, Transcription Factors |
| Protein Pathways : |
Neurotrophin signaling pathway, p53 signaling pathway |
| Lysate QC : |
RT-qPCR; Western Blotting (WB) |
