Recombinant Full Length Human APOC1 Protein, C-Flag-tagged

• Cat.No.: APOC1-1786HFL
• Product Overview: Recombinant Full Length Human APOC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 6.6 kDa
• AA Sequence: MRLFLSLPVLVVVLSIVLEGPAPAQ GTPDVSSALDKLKEFGNTLEDKARE LISRIKQSELSAKMREWFSE TFQKVKEKLKIDS TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: APOC1 apolipoprotein C1 [ Homo sapiens (human) ]
• Official Symbol: APOC1
• Synonyms: Apo-CI; ApoC-I; apo-CIB; apoC-IB
• Gene ID: 341
• mRNA Refseq: NM_001645.5
• Protein Refseq: NP_001636.1
• MIM: 107710
• UniProt ID: P02654