- Human(1)
Native Human C5b,6 Complex Protein
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| Cat.No. : | C5b6-1537H |
| Product Overview : | Native Human C5b,6 Complex Protein was purified from normal human serum. |
| Description : | C5b,6 is a product of complement activation of C5 and an intermediate in the formation of the C5b-9 membrane attack complex (MAC) of complement. |
| Source : | Normal human serum |
| Species : | Human |
| Form : | Frozen liquid |
| Bio-activity : | >10,000 Units/mg for lysis of sheep erythrocytes. |
| Molecular Mass : | 285,000 Da (3 chains). C5b,6 is composed of two disulfide linked chains from C5b (105,000 and 75,000) and one unlinked chain from C6 (105,000). |
| Purity : | >90% by SDS-PAGE |
| Unit Definition : | One unit of lytic activity is defined as the amount of C5b,6 complex required to yield 50% lysis of 1.5x10^7 sheep erythrocytes when incubated for 30 minutes at 37 centigrade in a total reaction volume of 75 µL GVBE (10 mM EDTA) containing 500 ng C7, 500 ng C8, and 1000 ng C9. |
| Storage : | Store at -70 centigrade or below. Avoid freeze/thaw. |
| Storage buffer : | 10 mM HEPES, 120 mM NaCl, pH 7.2 |
| Official Symbol : | C5b,6 Complex |
