Native Sheep PTGS1 Protein PTGS1-58S

Native Sheep PTGS1 Protein

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Native Sheep PTGS1 Protein

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Cat.No. : PTGS1-58S
Product Overview : Native sheep PTGS1 protein without tag was isolated from ram seminal vesicles.
Description : This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein.
Source : Ram seminal vesicles
Species : Sheep
Molecular Mass : 70 kDa
Unit Definition : One unit of enzyme consumes one nanomole of oxygen per minute at 37 centigrade in 0.1 M TrisHCl buffer, pH 8.0, containing 100 μM arachidonate, 5 mM EDTA, and 2 mM phenol, and 1 μM hematin. The cyclooxygenase activity of COX-1 was measured at 37 centigrade by monitoring oxygen consumption using a Gilson Model 5/6 H oxygraph equipped with a Clark oxygen electrode.
Stability : ≥ 1 year
Storage : Store it at -80 centigrade
Storage Buffer : 80 mM Tris-HCl, pH 8.0, containing 0.3 mM DDC, 0.1% polysorbate 20, and 10% glycerol
SDS-PAGE Analysis of PTGS1 :

Lane 1: MW Markers; Lane 2: COX1 (2 μg); Lane 3: COX1 (5 μg).

Gene Name : PTGS1 prostaglandin-endoperoxide synthase 1 [ Ovis aries (sheep) ]
Official Symbol : PTGS1
Synonyms : PTGS1; prostaglandin-endoperoxide synthase 1; COX1; COX-1; PGHS-1; prostaglandin G/H synthase 1; PGH synthase 1; PHS 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin endoperoxide synthase
Gene ID : 443551
mRNA Refseq : NM_001009476
Protein Refseq : NP_001009476
UniProt ID : P05979

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