Native Sheep PTGS1 Protein

• Cat.No.: PTGS1-58S
• Product Overview: Native sheep PTGS1 protein without tag was isolated from ram seminal vesicles.

Specification

• Description: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein.
• Source: Ram seminal vesicles
• Species: Sheep
• Molecular Mass: 70 kDa
• Unit Definition: One unit of enzyme consumes one nanomole of oxygen per minute at 37 centigrade in 0.1 M TrisHCl buffer, pH 8.0, containing 100 μM arachidonate, 5 mM EDTA, and 2 mM phenol, and 1 μM hematin. The cyclooxygenase activity of COX-1 was measured at 37 centigrade by monitoring oxygen consumption using a Gilson Model 5/6 H oxygraph equipped with a Clark oxygen electrode.
• Stability: ≥ 1 year
• Storage: Store it at -80 centigrade
• Storage Buffer: 80 mM Tris-HCl, pH 8.0, containing 0.3 mM DDC, 0.1% polysorbate 20, and 10% glycerol

Gene Information

• Gene Name: PTGS1 prostaglandin-endoperoxide synthase 1 [ Ovis aries (sheep) ]
• Official Symbol: PTGS1
• Synonyms: PTGS1; prostaglandin-endoperoxide synthase 1; COX1; COX-1; PGHS-1; prostaglandin G/H synthase 1; PGH synthase 1; PHS 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin endoperoxide synthase
• Gene ID: 443551
• mRNA Refseq: NM_001009476
• Protein Refseq: NP_001009476
• UniProt ID: P05979