Recombiant Human MED1 Protein Lysate
| Cat.No. : |
MED1-01H |
| Product Overview : |
Recombiant Human MED1 Protein Lysate without tag was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
| Description : |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. |
| Source : |
HEK293T |
| Species : |
Human |
| Form : |
Lyophilized powder |
| Molecular Mass : |
168.3 kDa |
| Storage : |
Store at -20 centigrade. Once reconsituted, aliquot and store any remaining material at -20C to avoid repeated freeze-thaw cycles. |
| Reconstitution : |
This protein lysate can be reconsituted using SDS Sample Buffer. |
| Gene Name : |
MED1 mediator complex subunit 1 [ Homo sapiens (human) ] |
| Official Symbol : |
MED1 |
| Synonyms : |
MED1; mediator complex subunit 1; PBP; CRSP1; RB18A; TRIP2; PPARBP; CRSP200; DRIP205; DRIP230; PPARGBP; TRAP220; mediator of RNA polymerase II transcription subunit 1; ARC205; PPAR-binding protein; PPARG binding protein; TR-interacting protein 2; TRIP-2; activator-recruited cofactor 205 kDa component; p53 regulatory protein RB18A; peroxisome proliferator-activated receptor-binding protein; thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; vitamin D receptor-interacting protein 230 kD; vitamin D receptor-interacting protein complex component DRIP205 |
| Gene ID : |
5469 |
| mRNA Refseq : |
NM_004774 |
| Protein Refseq : |
NP_004765 |
| MIM : |
604311 |
| UniProt ID : |
Q15648 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
