Recombiant Human MED1 Protein Lysate

• Cat.No.: MED1-01H
• Product Overview: Recombiant Human MED1 Protein Lysate without tag was expressed in HEK293T cells.

Specification

• Species: Human
• Source: HEK293
• Description: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.
• Form: Lyophilized powder
• Molecular Mass: 168.3 kDa
• Storage: Store at -20 centigrade. Once reconsituted, aliquot and store any remaining material at -20C to avoid repeated freeze-thaw cycles.
• Reconstitution: This protein lysate can be reconsituted using SDS Sample Buffer.

Gene Information

• Gene Name: MED1 mediator complex subunit 1 [ Homo sapiens (human) ]
• Official Symbol: MED1
• Synonyms: MED1; mediator complex subunit 1; PBP; CRSP1; RB18A; TRIP2; PPARBP; CRSP200; DRIP205; DRIP230; PPARGBP; TRAP220; mediator of RNA polymerase II transcription subunit 1; ARC205; PPAR-binding protein; PPARG binding protein; TR-interacting protein 2; TRIP-2; activator-recruited cofactor 205 kDa component; p53 regulatory protein RB18A; peroxisome proliferator-activated receptor-binding protein; thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; vitamin D receptor-interacting protein 230 kD; vitamin D receptor-interacting protein complex component DRIP205
• Gene ID: 5469
• mRNA Refseq: NM_004774
• Protein Refseq: NP_004765
• MIM: 604311
• UniProt ID: Q15648