Recombinant Active Human GDF2 Protein, His-tagged(N-ter)
Cat.No. : | GDF2-104H |
Product Overview : | Recombinant Active Human GDF2 Protein with His tag (N-ter) was expressed in E. coli. |
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Description : | The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jan 2014] |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Powder |
Bio-activity : | Determined by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is < 0.4 ng/mL. |
AA Sequence : | SAGAGSHCQKTSLRVNFEDIGWDSW IIAPKEYEAYECKGGCFFPLADDVT PTKHAIVQTLVHLKFPTKVGKACCV PTKLSPISVLYKDDMGVPTLKYHYE GMSVAECGCR |
Endotoxin : | Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 98% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | 20 mM Sodium citrate (pH 3.5) and 0.2 M NaCl. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Gene Name : | GDF2 growth differentiation factor 2 [ Homo sapiens ] |
Official Symbol : | GDF2 |
Synonyms : | GDF2; growth differentiation factor 2; growth/differentiation factor 2; BMP 9; BMP9; GDF-2; bone morphogenetic protein 9; BMP-9; |
Gene ID : | 2658 |
mRNA Refseq : | NM_016204 |
Protein Refseq : | NP_057288 |
MIM : | 605120 |
UniProt ID : | Q9UK05 |
Products Types
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◆ Lysates | ||
GDF2-5970HCL | Recombinant Human GDF2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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