Recombinant Active Mouse IL36G Protein, His-tagged(C-ter)
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Cat.No. : | Il36g-199M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Active Mouse IL36G Protein with His tag (C-ter) was expressed in E. coli. |
Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] |
Source : | E. coli |
Species : | Mouse |
Tag : | His(C-ter) |
Form : | Powder |
Bio-activity : | Determined by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is < 15 ng/mL. The specific activity of recombinant mouse IL-36 gamma is > 6 x 10^4 IU/mg. |
AA Sequence : | MGRETPDFGE VFDLDQQVWI FRNQALVTVP RSHRVTPVSV TILPCKYPES LEQDKGIAIY LGIQNPDKCL FCKEVNGHPT LLLKEEKILD LYHHPEPMKP FLFYHTRTGG TSTFESVAFP GHYIASSKTG NPIFLTSKKG EYYNINFNLD IKS |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 98% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 7.4) |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
SDS-PAGE : |
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Gene Name : | Il36g interleukin 36G [ Mus musculus (house mouse) ] |
Official Symbol : | Il36g |
Synonyms : | Il36g; interleukin 36G; If36g; Il1f9; IL-36gamma; |
Gene ID : | 215257 |
mRNA Refseq : | NM_153511 |
Protein Refseq : | NP_705731 |
UniProt ID : | Q3U0P4 |
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Il36g-1865R | Recombinant Rat Il36g protein, His & T7-tagged | +Inquiry |
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◆ Lysates
IL36G-5235HCL | Recombinant Human IL1F9 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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