Recombinant Bat coronavirus HKU4 NSP5 Protein (S3292-Q3597), His-tagged

• Cat.No.: NSP5-1491B
• Product Overview: Recombinant Bat coronavirus HKU4 6His-TEV-(G)-HKU4-NSP5(S3292-Q3597) protein with a His tag was expressed in E. coli

Specification

• Species: BtCoV
• Source: E.coli
• Tag: His
• Protein Length: S3292-Q3597
• Description: The papain-like proteinase (PL-PRO) is responsible for the cleavages located at the N-terminus of replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48' and 'Lys-63' linked polyubiquitin chains from cellular substrates. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF-3.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Official Symbol: pp1a
• Synonyms: Replicase polyprotein 1a; Replicase polyprotein 1a; pp1a; ORF1a polyprotein
• UniProt ID: P0C6T4