Active Recombinant SARS-CoV2 3CL Protease, His-tagged
Cat.No. : | nsp5-106S |
Product Overview : | Recombinant 3-chymotrypsin-like (3CL) protease of the novel coronavirus (SARS-CoV2), a monomeric polypeptide of 317 (306+11) amino acids, with His at C-terminus was expressed in E. coli cells and purified by an affinity column in combination of other chromatograph methods. |
- Specification
- Gene Information
- Related Products
Description : | Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has been attributed to a novel coronavirus (SARS CoV). The SARS 3C like protease (SARS 3CL(pro)) is a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an attractive target for therapeutics against SARS. |
Source : | E. coli |
Species : | SARS-CoV-2 |
Tag : | His |
Bio-activity : | Recombinant 3CL protease of SARS-CoV2 is suitable for screening its inhibitors and other related function assays. |
Molecular Mass : | 34 kDa |
AA Sequence : | MMSGFRKMAFPSGKVEGCMVQVTCG TTTLNGLWLDDVVYCPRHVICTSED MLNPNYEDLLIRKSNHNFLVQAGNV QLRVIGHSMQNCVLKLKVDTANPKT PKYKFVRIQPGQTFSVLACYNGSPS GVYQCAMRPNFTIKGSFLNGSCGSV GFNIDYDCVSFCYMHHMELPTGVHA GTDLEGNFYGPFVDRQTAQAAGTDT TITVNVLAWLYAAVINGDRWFLNRF TTTLNDFNLVAMKYNYEPLTQDHVD ILGPLSAQTGIAVLDMCASLKELLQ NGMNGRTILGSALLEDEFTPFDVVR QCSGVTFQGGGHHHHHH* |
Purity : | ≥ 90%, as determined by SDS-PAGE. |
Storage : | The protein sample can be stored under sterile conditions at 2-8 centigrade for one month or at -20 to -70 centigrade for three months without detectable loss of activity. |
Storage Buffer : | Formulation 20 mM Tris-Cl, pH7.9, 20% glycerol, 100 mM NaCl, 1 mM DTT and 0.5 mM EDTA. |
Official Symbol : | nsp5 |
Synonyms : | 3CL; 3C-like proteinase; 3CL PRO; 3CLp; nsp5 |
Protein Refseq : | YP_009725301 |
Official Symbol : | nsp5 |
Synonyms : | 3CL; 3C-like proteinase; 3CL PRO; 3CLp; nsp5 |
Protein Refseq : | YP_009725301 |
Products Types
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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