Recombinant Bordetella Pertussis PTXA Protein (35-269 aa), His-tagged
| Cat.No. : | PTXA-1609B |
| Product Overview : | Recombinant Bordetella Pertussis (strain Tohama I/ATCC BAA-589/NCTC 13251) PTXA Protein (35-269 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
- Related Products
| Description : | S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their mbrane receptors. |
| Source : | Yeast |
| Species : | Bordetella Pertussis |
| Tag : | His |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 28.2 kDa |
| Protein length : | 35-269 aa |
| AA Sequence : | DDPPATVYRYDSRPPEDVFQNGFTA WGNNDNVLDHLTGRSCQVGSSNSAF VSTSSSRRYTEVYLEHRMQEAVEAE RAGRGTGHFIGYIYEVRADNNFYGA ASSYFEYVDTYGDNAGRILAGALAT YQSEYLAHRRIPPENIRRVTRVYHN GITGETTTTEYSNARYVSQQTRANP NPYTSRRSVASIVGTLVRMAPVIGA CMARQAESSEAMAAWSERAGEAMVL VYYESIAYSF |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Gene Name : | ptxA pertussis toxin subunit 1 [ Bordetella pertussis Tohama I ] |
| Official Symbol : | PTXA |
| Synonyms : | ptxA; Islet-activating protein S1; IAP S1NAD-dependent ADP-ribosyltransferase (EC:2.4.2.-); |
| Gene ID : | 2665068 |
| Protein Refseq : | NP_882282 |
| UniProt ID : | P04977 |
Products Types
| ◆ Recombinant Protein | ||
| PTXA-938B | Recombinant Bordetella Pertussis PTXA Protein (35-269 aa), His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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