Recombinant Bovine CDK5R1, GST-tagged
Cat.No. : | CDK5R1-687B |
Product Overview : | Recombinant bovine cleaved Cdk5 activator (p35) fused to GST was expressed inE. coli.It is produced as a 35 kDa precursor and further cleaved into the 25 kDa form of the protein. MW = 51 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDK5R1-687B |
Description : | Cleaved Cdk5 activator is an essential regulating subunit of cdk5. Aberrant Cdk5 activity has been implicated in a number of neurodegenerative diseases such as Alzheimer"s disease, amyotrophic lateral sclerosis, and Parkinson"s disease, where abnormal phosphorylation of tau and/or neurofilaments has been observed. One vial contains sufficient material for approximately 25 reactions. |
Source : | E. coli. |
Form : | Liquid. In 25 mM Tris-HCl, 100 µM DTT, 30% glycerol, pH 7.4. Please refer to vial label for lot-specific concentration. |
Unit Definition : | One unit is defined as the amount of protein that when reconstituted with Cdk5 will transfer 1 pmol of phosphate to Histone H1 peptide (9-18) per min at 30°C, pH 7.2. |
Specific Activity : | ≥100,000 units/mg protein. |
Toxicity : | Standard Handling (MSDS available upon request). |
Storage : | -20°C . Avoid freeze/thaw Following initial thaw, aliquot and freeze (-20°C). |
Gene Name : | CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) [ Bos taurus ] |
Synonyms : | cyclin-dependent kinase 5, regulatory subunit 1 (p35); P25/P35; cyclin-dependent kinase 5 activator 1; p23; CDK5 activator 1; TPKII regulatory subunit; tau protein kinase II 23 kDa subunit; cyclin-dependent kinase 5 regulatory subunit 1 |
Gene ID : | 282173 |
mRNA Refseq : | NM_174512 |
Protein Refseq : | NP_776937 |
UniProt ID : | Q28199 |
Chromosome Location : | 19 |
Pathway : | Alzheimer"s disease |
Function : | cadherin binding; calcium ion binding; kinase activity; protein binding; cyclin-dependent protein kinase 5 activator activity; protein serine/threonine kinase activator activity |
Products Types
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◆ Lysates | ||
CDK5R1-7625HCL | Recombinant Human CDK5R1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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