Recombinant Bovine Chemokine (C-C motif) Ligand 5 CCL5-132B

Recombinant Bovine Chemokine (C-C motif) Ligand 5


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Cat.No. : CCL5-132B Optional Service: Optional requirements on this protein
Product Overview : Recombinant Bovine CCL5 protein was expressed inYeastand purified by using Ion-exchange chromatography, 7.9 kDa (68 aa).
Description : CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e., IL-2 and IFN-γ) that are released by T cells, CCL5 also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells.
Source : Yeast.
Formulation/Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purity : >95% as visualized by SDS-PAGE analysis.
Purification : Ion-exchange chromatography.
Biological Activity : In testing.
Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Pathways : Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; NOD-like receptor signaling pathway; Prion diseases; Toll-like receptor signaling pathway
PDB rendering based on 1pmi :

Gene Name : CCL5 chemokine (C-C motif) ligand 5 [ Bos taurus ]
Synonyms : CCL5; chemokine (C-C motif) ligand 5; RANTES; MGC127014; C-C motif chemokine 5; SIS-delta; small-inducible cytokine A5; T-cell-specific protein RANTES
Gene ID : 327712
mRNA Refseq : NM_175827
Protein Refseq : NP_787021
UniProt ID : O97919
Chromosome Location : 19
Function : chemoattractant activity; chemokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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