Recombinant Bovine ICAM1 Protein

• Cat.No.: ICAM1-4320B
• Product Overview: Recombinant Bovine ICAM1 Protein (453aa) was expressed in yeast.

Specification

• Source: Yeast
• Species: Bovine
• Form: Lyophilized
• Molecular Mass: 50.0 kDa
• Protein length: 453aa
• AA sequence: GISIHPSKAI IPRGDSLTVN CSNSCDQKST FGLETVLIKE EVGRGDNWKV FQLRDVQEDI ELFCYSNCHK EQTIASMNLT VYWFPEHVEL APLPLWQPVG EELNLSCLVS GGAPRAHLSV VLLRGEEELG RQPVGKGEPA KVMFTVQSRR EDHGTNFSCR WELDLRSQGL ELFQNTSAPR KLQTYVLPSI DPHLEVPPIV EVGSRWPVNC TLDGLFPASD AKVYLVLGDQ KLESNITYDG DSVLAKAWME ENEEGTHSLK CSVTLGEVSR RTQENVTVYS FPLPTLTLSP PEVSEWTTVT VECVTRDGAV VKLNGTSAVP PGPRAQLKLN ASASDHRSNF SCSAALEIAG QVVHKHQTLE LHVLYGPRLD QRDCPGNWTW QEGSEQTLKC EAQGNPIPKL NCSRKGDGAS LPIGDLRPVR REVAGTYLCR ATSARGRVTR EVVLNVLHGQ NIL (453)
• Purity: >95% as visualized by SDS-PAGE analysis.
• Applications: This endotoxin-free recombinant protein can be used in cell culture, ELISA Standard, and as a Western Blot Control.
• Storage: Store at -20 centigrade.
• Tag: Non

Gene Information

• Gene Name: ICAM1 intercellular adhesion molecule 1 [ Bos taurus (cattle) ]
• Official Symbol: ICAM1
• Synonyms: intercellular adhesion molecule 1; ICAM-1
• Gene ID: 281839
• mRNA Refseq: NM_174348.2
• Protein Refseq: NP_776773.1
• UniProt ID: Q95132

Reviews

04/27/2022

Manufacturers may provide documentation of the protein's validation, which includes information about its purity, concentration, stability, and potential contaminants.

11/05/2020

This can be particularly important in clinical trials to ensure accurate and reliable results.

10/14/2016

If the need arises for larger quantities of ICAM1 protein during the later stages of clinical trials, the manufacturer can facilitate scale-up production processes to meet those requirements.

Q&As

Can ICAM1 be a potential therapeutic target?

Yes, targeting ICAM1 is being explored as a potential therapeutic strategy for inflammatory diseases, with research focusing on developing ICAM1 inhibitors.

How is ICAM1 involved in inflammation?

ICAM1 is upregulated during inflammation, promoting the adhesion of immune cells to the endothelium and facilitating their migration into inflamed tissues.

How is ICAM1 involved in cancer progression?

ICAM1 expression can be altered in cancer cells and is implicated in promoting cancer progression by facilitating tumor cell adhesion, invasion, and metastasis.

Are there diagnostic applications for ICAM1 in clinical settings?

ICAM1 levels can be measured in blood or tissue samples, and elevated levels may serve as diagnostic markers for certain inflammatory diseases.

Can ICAM1 be used as a prognostic marker in certain diseases?

Elevated levels of ICAM1 in some diseases may serve as prognostic markers, indicating disease severity and potential outcomes.