Recombinant Bovine Phosphoinositide-3-Kinase, Catalytic, Alpha Polypeptide, GST-tagged
Cat.No. : | PIK3CA-1864B |
Product Overview : | Recombinant BovinePIK3CA was expessed in Sf9 insect cells with a GST-tag. |
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Cat. No. : | PIK3CA-1864B |
Description : | The PIK3CA andregulatory subunits are co-expressed in Sf9 insect cells. The catalyticsubunit carries a GST-Tag and the heterodimer was purified by affinitychromatography. The GST-Tag facilitates the protein's application in typicalGST pulldown assays. The MW of p110 alpha is 124.3 kDa (without Tag). The MWof p85 alpha is 83.5 kDa. |
Source : | Sf9 insect cells |
Species : | Bovine |
Form : | Liquid supplied in25 mM Tris, pH 8.0 + 50 mM NaCl + 0.5 mM MgCl2 + 50% glycerol. |
Concentration : | 0.5 mg/ml |
Biological Activity : | 3 nmol/mg/min usingphosphatidylinositol as the substrate. |
Storage : | When stored at-20°C, this product is stable for one year. Avoid repeated freeze-thawcycles. |
OfficialSymbol : | PIK3CA |
Gene Name : | PIK3CA phosphoinositide-3-kinase,catalytic, alpha polypeptide [ Bos taurus ] |
Synonyms : | PIK3CA;phosphoinositide-3-kinase, catalytic, alpha polypeptide;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphaisoform; PI3K; PI3Kalpha; p110alpha; PI3K-alpha; ptdIns-3-kinase p110;PI3-kinase subunit alpha; PI3-kinase p110 subunit alpha; ptdIns-3-kinasesubunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine proteinkinase PIK3CA; phosphoinositide-3-kinase catalytic alpha polypeptide;phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunitalpha; EC 2.7.1.153; EC 2.7.11.1; MGC142161; MGC142163; p110-alpha |
Gene ID : | 282306 |
mRNA Refseq : | NM_174574 |
Protein Refseq : | NP_776999 |
UniProt ID : | P32871 |
Pathway : | Acute myeloidleukemia; Apoptosis; B cell receptor signaling pathway; Chemokine signalingpathway; Colorectal cancer; Endometrial cancer; Fc epsilon RI signalingpathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Inositol phosphatemetabolism; Insulin signaling pathway; Jak-STAT signaling pathway; Leukocytetransendothelial migration; Natural killer cell mediated cytotoxicity;Neurotrophin signaling pathway |
Function : | 1-phosphatidylinositol-3-kinaseactivity; ATP binding; inositol or phosphatidylinositol kinase activity;insulin receptor substrate binding; nucleotide binding; phosphatidylinositol-4,5-bisphosphate3-kinase activity; phosphotransferase activity, alcohol group as acceptor;transferase activity; protein binding; protein kinase activator activity;protein serine/threonine kinase activity |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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