Recombinant C. difficile tcdB Protein
| Cat.No. : | tcdB-007C |
| Product Overview : | Recombinant Clostridioides difficile tcdB protein without tag was expressed in E.coli |
- Specification
- Gene Information
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| Description : | Toxin B from Clostridium difficile, also known as TcdB, is a cytotoxin that has glucosyltransferase and cysteine protease activities. It inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion. Toxin B can induce activation of the inflammasome and apoptosis. While both toxin A and toxin B inactivate Rho family GTPases, toxin B more potently induces mammalian cell rounding in culture. |
| Source : | E. coli |
| Species : | C. difficile |
| Purity : | ≥90% estimated by SDS-PAGE |
| Stability : | ≥ 2 years |
| Storage : | 2 to 8 centigrade |
| Concentration : | 0.2 mg/ml |
| Storage Buffer : | Each vial contains 50 μg of C. difficile toxin B in 50 mM Tris, 100 mM NaCl, pH 7.5 |
| Shipping : | Room Temperature in continental US, may vary elsewhere. |
| Gene Name : | tcdB glycosylating toxin TcdB [ Clostridioides difficile ] |
| Official Symbol : | tcdB |
| Synonyms : | tcdB; glycosylating toxin TcdB; toxB; glycosylating toxin TcdB |
| Gene ID : | 31352216 |
| UniProt ID : | P18177 |
Products Types
| ◆ Native Protein | ||
| TcdB-189C | Active Native Clostridium difficile Toxin B Protein | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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