Recombinant C. difficile tcdB Protein tcdB-007C

Recombinant C. difficile tcdB Protein

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Recombinant C. difficile tcdB Protein

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Cat.No. : tcdB-007C
Product Overview : Recombinant Clostridioides difficile tcdB protein without tag was expressed in E.coli
Description : Toxin B from Clostridium difficile, also known as TcdB, is a cytotoxin that has glucosyltransferase and cysteine protease activities. It inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion. Toxin B can induce activation of the inflammasome and apoptosis. While both toxin A and toxin B inactivate Rho family GTPases, toxin B more potently induces mammalian cell rounding in culture.
Source : E. coli
Species : C. difficile
Purity : ≥90% estimated by SDS-PAGE
Stability : ≥ 2 years
Storage : 2 to 8 centigrade
Concentration : 0.2 mg/ml
Storage Buffer : Each vial contains 50 μg of C. difficile toxin B in 50 mM Tris, 100 mM NaCl, pH 7.5
Shipping : Room Temperature in continental US, may vary elsewhere.
Gene Name : tcdB glycosylating toxin TcdB [ Clostridioides difficile ]
Official Symbol : tcdB
Synonyms : tcdB; glycosylating toxin TcdB; toxB; glycosylating toxin TcdB
Gene ID : 31352216
UniProt ID : P18177

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