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Active Recombinant Canine IL6R protein, His-tagged

Cat.No. : IL6R-1064C
Product Overview : Recombinant Canine IL6R protein(XP_855105.1)(Met1-Pro365), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Canine
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : 1.Measured by its binding ability in a functional ELISA.2.Immobilized canine IL6R-His at 10μg/mL (100μL/well) can bind human IL6, the EC50 of human IL6 is 5-50 ng/mL.
Molecular Mass : The recombinant canine IL6R consists 357 amino acids and predicts a molecular mass of 39.8 kDa.
Protein Length : Met1-Pro365
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the dose and route of administration of IL6R? 04/30/2022

The dose and route of administration need to be determined according to the specific treatment situation. Common routes of administration include subcutaneous injection and intravenous injection.

Can recombinant IL6R be used in autoimmune diseases? 04/03/2022

It can be used to treat certain autoimmune diseases, such as rheumatoid arthritis and psoriasis.

Can recombinant IL6R be used to prevent disease? 09/14/2021

The IL6R is primarily used to treat inflammatory diseases that have already occurred, rather than prevent them.

How the action mechanism of IL6R? 03/20/2021

IL6R reduces inflammation by binding to interleukin-6 (IL-6), blocking the IL-6 signaling pathway.

Does IL6R have anti-tumor effects? 11/06/2020

Although IL6R can regulate the immune system, it is not a direct anti-tumor drug.

How to evaluate the efficacy of IL6R? 06/29/2019

The efficacy of IL6R is usually evaluated based on improvement of clinical symptoms, changes in disease activity, and changes in biochemical markers.

Customer Reviews (3)

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Reviews
02/23/2022

    Good compatibility and stability with the surfactant.

    11/23/2020

      Expression level and stability of clones were good.

      02/01/2019

        Remarkable antibacterial activity and bactericidal effect on bacteria.

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