Recombinant Canine Interleukin 8

• Cat.No.: IL8-245C
• Product Overview: Recombinant Canine IL8 was expressed inYeast. MW= 8.6 kDa (74 aa).

Specification

• Species: Canine
• Source: Yeast
• Tag: Non
• Description: Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purification: Ion-exchange chromatography.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Amino Acid Sequence: VSSELRCQCI KTHSTPFHPK YIKELRVIDS GPHCENSEII VKLFNGNEVC LDPKEKWVQK VVQIFLKKAE KQDP.
• Bioactivity: In testing.
• Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: IL8 interleukin 8 [ Canis lupus familiaris ]
• Synonyms: interleukin 8; IL8; IL-8; interleukin-8; C-X-C motif chemokine 8
• Gene ID: 403850
• mRNA Refseq: NM_001003200.1
• Protein Refseq: NP_001003200.1
• UniProt ID: P41324
• Chromosome Location: 13
• Pathway: Bladder cancer; Chemokine signaling pathway; Cytokine-cytokine receptor interaction; NOD-like receptor signaling pathway; Pathways in cancer; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway