Recombinant Canis lupus DUT protein, His-tagged
Cat.No. : | DUT-12C |
Product Overview : | Recombinant Canis lupus DUT fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Canis lupus |
Tag : | His |
Form : | 20 mM Tris-HCl, 0.15 M NaCl, pH 8.0 |
Molecular Mass : | ~18.136 kDa |
AA Sequence : | MGHHHHHHTPAISPSKRARPAEDGM RLRFVRLSEHATAPTKGSPRAAGYD LYSAYDYILPPMEKAIVKTDIQVAL PSGCYGRVAPRSGLAAKHFIDVGAG VIDEDYRGNVGVVLFNFGKEKFEVK KGDRIAQLICERIFYPEIEEVQVLD DTERGSGGFGSTGKN |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | >95% by SDS-PAGE |
Gene Name : | DUT deoxyuridine triphosphatase [ Canis lupus familiaris ] |
Official Symbol : | DUT |
Synonyms : | deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; dUTP pyrophosphatase |
Gene ID : | 609526 |
Chromosome Location : | chromosome: 30 |
Pathway : | Metabolic pathways, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem |
Products Types
◆ Recombinant Protein | ||
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DUT-1979R | Recombinant Rat Dut protein, His-tagged | +Inquiry |
DUT-791H | Recombinant Human DUT protein, His-tagged | +Inquiry |
DUT-27878TH | Recombinant Human DUT, His-tagged | +Inquiry |
◆ Lysates | ||
DUT-6768HCL | Recombinant Human DUT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (5)
Ask a questionYes, alterations in the expression levels of the DUT protein can serve as a biomarker for certain cancers, aiding in early diagnosis and prognosis.
Research suggests a link between the DUT protein and neurodegenerative diseases, where its dysfunction may impact DNA repair processes in neurons, potentially contributing to disease progression.
Research suggests that the DUT protein is particularly relevant in colorectal cancer, where its abnormal expression may impact DNA replication and repair mechanisms.
The DUT protein is implicated in cancer research as its dysregulation can lead to an imbalance in nucleotide pools, potentially contributing to genomic instability, a common feature in cancer cells.
Understanding the role of the DUT protein helps in developing targeted therapies that aim to modulate its activity, potentially disrupting cancer cell proliferation.
Customer Reviews (3)
Write a reviewThe DUT protein demonstrates significant relevance and potential in various trial applications, primarily focusing on inflammation, angiogenesis, and tissue remodeling.
Another advantage of the DUT protein is its reliability and consistency, ensuring robust and reproducible results.
Whether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.
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