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Recombinant Canis lupus DUT protein, His-tagged

Cat.No. : DUT-12C
Product Overview : Recombinant Canis lupus DUT fused with His tag was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Canis lupus
Tag : His
Form : 20 mM Tris-HCl, 0.15 M NaCl, pH 8.0
Molecular Mass : ~18.136 kDa
AA Sequence : MGHHHHHHTPAISPSKRARPAEDGM RLRFVRLSEHATAPTKGSPRAAGYD LYSAYDYILPPMEKAIVKTDIQVAL PSGCYGRVAPRSGLAAKHFIDVGAG VIDEDYRGNVGVVLFNFGKEKFEVK KGDRIAQLICERIFYPEIEEVQVLD DTERGSGGFGSTGKN
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : >95% by SDS-PAGE
Gene Name : DUT deoxyuridine triphosphatase [ Canis lupus familiaris ]
Official Symbol : DUT
Synonyms : deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; dUTP pyrophosphatase
Gene ID : 609526
Chromosome Location : chromosome: 30
Pathway : Metabolic pathways, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can the DUT protein be used as a biomarker in cancer diagnosis? 03/08/2022

Yes, alterations in the expression levels of the DUT protein can serve as a biomarker for certain cancers, aiding in early diagnosis and prognosis.

How does the DUT protein contribute to the understanding of neurodegenerative diseases? 10/12/2020

Research suggests a link between the DUT protein and neurodegenerative diseases, where its dysfunction may impact DNA repair processes in neurons, potentially contributing to disease progression.

Are there any specific cancer types where the DUT protein is particularly relevant? 01/14/2020

Research suggests that the DUT protein is particularly relevant in colorectal cancer, where its abnormal expression may impact DNA replication and repair mechanisms.

How is the DUT protein clinically significant in cancer research? 09/07/2019

The DUT protein is implicated in cancer research as its dysregulation can lead to an imbalance in nucleotide pools, potentially contributing to genomic instability, a common feature in cancer cells.

How does the DUT protein contribute to the development of targeted therapies in cancer treatment? 03/19/2016

Understanding the role of the DUT protein helps in developing targeted therapies that aim to modulate its activity, potentially disrupting cancer cell proliferation.

Customer Reviews (3)

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Reviews
04/01/2021

    The DUT protein demonstrates significant relevance and potential in various trial applications, primarily focusing on inflammation, angiogenesis, and tissue remodeling.

    04/21/2020

      Another advantage of the DUT protein is its reliability and consistency, ensuring robust and reproducible results.

      05/12/2017

        Whether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.

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