Recombinant Cervid PRNP protein, His-tagged
Cat.No. : | PRP-02C |
Product Overview : | Recombinant Cervid PRNP Protein with a His tag was expressed in E. coli. |
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Description : | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Cervid |
Tag : | His |
Molecular Mass : | ~ 17.3 kDa, reducing conditions |
AA Sequence : | MGGGWGQSGTHSQWNKPSKPKTNMK HVAGAAAAGAVVGGLGGYMLGSAMS RPLIHFGNDYEDRYYRENMYRYPNQ VYYRPVDQYNNQNTFVHDCVNITVK QHTVTTTTKGENFTETDIKMMERVV EQMCITQYQRESQAYYQLEHHHHHH |
Purity : | > 90% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.12 mg/mL |
Storage Buffer : | Supplied as a 0.2 μm filtered solution in PBS, pH 8.0 |
Gene Name : | PRNP prion protein [ Cervus canadensis ] |
Official Symbol : | PRNP |
Synonyms : | PRNP; prion protein; PrP; major prion protein; prion protein PrP |
Gene ID : | 122448236 |
mRNA Refseq : | XM_043479407 |
Protein Refseq : | XP_043335342 |
UniProt ID : | P79142 |
Products Types
◆ Recombinant Protein | ||
PRNP-555C | Recombinant Cynomolgus Monkey PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PRNP-4367R | Recombinant Rat PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PRNP-7129M | Recombinant Mouse PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PRNP-118H | Recombinant Human PRNP Protein, His-tagged | +Inquiry |
PRNP-3435R | Recombinant Rhesus Macaque PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRNP-001HCL | Recombinant Human PRNP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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