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Recombinant Chicken IL-15

Cat.No. : IL15-20C
Product Overview : Chicken IL-15 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
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  • Gene Information
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Description : Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 was discovered to be a member of a family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-21. The specific receptor for IL-15, IL-15 receptor alpha, appears to regulate IL-15 secretion, stability, and activity. All members of this family use the common gamma chain as part of their signaling complex. IL-15 has been shown to play a role in many diseases, including obesity, influenza, and inflammatory autoimmune diseases.
Source : Yeast
Species : Chicken
Form : Lyophilized
Molecular Mass : 14.5 kDa
AA Sequence : NHCKWSDVLK DLELIKTSED IDVSLYTANT YEDIECQEPV MRCFFLEMKV ILHECDIKKC SRKHDVRNIW KNGNARFATY QLNSTTAKKC KECEEYEEKN FTEFIQSFVK VIQRECKKYA N (121)
Applications : The chicken IL-15 protein can be used in cell culture, as an IL-15 ELISA Standard, and as a Western Blot Control.
Storage : -20 C

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What techniques differentiate IL15 and IL2 receptor binding kinetics? 10/22/2022

Techniques discern IL15 and IL2 receptor binding kinetics.

What experimental methods study IL15's involvement in autoimmune diseases? 06/23/2022

Methods explore IL15's role in autoimmune disease mechanisms.

What are the applications of IL15 knockout models in deciphering its functions? 04/26/2022

IL15 knockout models provide insights into its diverse functions.

How do you analyze IL15's impact on memory T cell differentiation? 09/19/2021

IL15's influence on memory T cell differentiation investigated.

How does immunofluorescence microscopy visualize IL15 localization in cells? 07/26/2021

Immunofluorescence microscopy visualizes IL15 subcellular localization.

What approaches validate IL15's role in inflammatory responses? 02/04/2021

Approaches validate IL15's involvement in inflammatory responses.

Could you explain the role of IL15 in NK cell cytotoxicity assays? 10/26/2019

IL15's role in NK cell cytotoxicity analyzed using assays.

Can you detail the use of ELISA in quantifying IL15 secretion? 02/03/2018

ELISA measures IL15 secretion accurately.

How is IL15's effect on regulatory T cells quantified using qPCR? 06/08/2017

qPCR quantifies IL15's impact on regulatory T cells.

How does flow cytometry assess IL15-induced T-cell proliferation? 05/26/2017

Flow cytometry quantifies IL15-driven T-cell proliferation.

Customer Reviews (3)

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Reviews
04/19/2018

    Mapping protein- interactions in DNA transcription for gene regulation.

    02/20/2018

      Suitable for cytotoxicity assays.

      10/22/2017

        Effective in NK cell activation.

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