Recombinant Chicken IL5 Protein, His-tagged
Cat.No. : | IL5-1044C |
Product Overview : | Recombinant Chicken IL5 Protein (Thr17-Val136) with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2. This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Source : | E. coli |
Species : | Chicken |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 17.7 kDa; Accurate Molecular Mass: 15 kDa |
Protein length : | Thr17-Val136 |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | IL5 interleukin 5 [ Gallus gallus (chicken) ] |
Official Symbol : | IL5 |
Synonyms : | IL5; interleukin 5; interleukin-5; TRF; BCGF-II; B-cell growth factor II; T-cell replacing factor; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; Il-5; |
Gene ID : | 474360 |
mRNA Refseq : | NM_001007084 |
Protein Refseq : | NP_001007085 |
UniProt ID : | Q5W4T8 |
Products Types
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◆ Lysates | ||
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionInhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.
IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.
Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.
Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.
IL5 cannot be administered orally, only by injection or intravenous drip.
IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.
Customer Reviews (3)
Write a reviewHigh efficacy and safety in clinical treatment.
There are no structural or functional defects.
The stability and activity are maintained well during long-term storage.
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