Recombinant Cynomolgus CD46 protein, His-tagged
Cat.No. : | CD46-1486C |
Product Overview : | Recombinant Cynomolgus CD46 protein(A0A2K5WCS2)(Cys35-Asp329), fused with C-terminal His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Cynomolgus |
Tag : | C-His |
Protein length : | Cys35-Asp329 |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Cynomolgus CD46, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.67μg/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 34.05 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC. |
Storage : | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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◆ Lysates | ||
CD46-1964HCL | Recombinant Human CD46 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.
With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.
Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.
Q&As (5)
Ask a questionCD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.
Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.
CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.
Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.
CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.
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