Recombinant Cynomolgus FAP protein, His-Avi-tagged, Biotinylated
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | FAP-377CB Optional Service: Optional requirements on this protein |
Product Overview : | Biotinylated Cynomolgus FAP, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Leu 26 - Asp 760 (Accession # XP_005573377). |
Description : | FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner. |
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | His-Avi |
Predicted N Terminal : | His |
Form : | Please contact us for detailed information. |
Molecular Mass : | The protein has a calculated MW of 88.6 kDa. |
Protein length : | Leu 26 - Asp 760 |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
Gene Name : | FAP fibroblast activation protein alpha [ Macaca fascicularis (crab-eating macaque) ] |
Official Symbol : | FAP |
Synonyms : | FAP; FAPalpha; SIMP; Seprase; APCE |
Gene ID : | 102134935 |
mRNA Refseq : | XM_005573320.2 |
Protein Refseq : | XP_005573377.1 |
◆ Recombinant Protein
Fap-716M | Recombinant Mouse Fap Protein, His-tagged | +Inquiry |
FAP-3836H | Recombinant Human FAP Protein, GST-tagged | +Inquiry |
Fap-1018M | Recombinant Mouse Fap Protein, MYC/DDK-tagged | +Inquiry |
FAP-006H | Recombinant Human FAP Protein, His-tagged | +Inquiry |
FAP-371H | Recombinant Human FAP Protein, His-tagged | +Inquiry |
|
◆ Lysates
FAP-1881HCL | Recombinant Human FAP cell lysate | +Inquiry |
|
◆ Assay kits
Kit-1729 | FAP Assay Kit | +Inquiry |
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy