Active Recombinant Cynomolgus IFNGR1 Protein, Fc-tagged

• Cat.No.: IFNGR1-1207C
• Product Overview: Recombinant cynomolgus IFNGR1 (G7P327) (Met1-Gly245) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Cynomolgus
• Tag: Fc
• Predicted N Terminal: Glu 18
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized Cynomolgus IFNG at 10 μg/ml (100 μl/well) can bind Cynomolgus IFNGR1-Fc. The EC50 of Cynomolgus IFNGR1-Fc is 20.28-47.32 ng/ml.
• Molecular Mass: The recombinant cynomolgus IFNGR1 is a disulfide-linked homodimer. The reduced monomer comprises 469 amino acids and has a calculated molecular mass of 52.8 KDa.The apparent molecular mass of the protein is approximately 63 KDa respectively in SDS-PAGE.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IFNGR1 interferon gamma receptor 1 [ Macaca fascicularis ]
• Official Symbol: IFNGR1
• Synonyms: interferon gamma receptor 1
• Gene ID: 101866179
• mRNA Refseq: NM_001284940
• Protein Refseq: NP_001271869
• Chromosome Location: chromosome: 4
• Pathway: Chagas disease (American trypanosomiasis), organism-specific biosystem; Herpes simplex infection, conserved biosystem; Inflammatory bowel disease (IBD), conserved biosystem