Description : |
IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically ass centigradeiated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20. |
Source : |
HEK293 |
Species : |
Cynomolgus |
Tag : |
Fc |
Predicted N Terminal : |
Asp 30 |
Form : |
Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : |
The recombinant cynomolgus IL20RB consists of 439 amino acids and predicts a molecular mass of 49.2 kDa. |
Protein length : |
Asp30-Ala230 |
Endotoxin : |
< 1.0 EU per μg protein as determined by the LAL method. |
Purity : |
> 90 % as determined by SDS-PAGE. |
Storage : |
Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Official Symbol : |
IL20RB |
Synonyms : |
IL20RB;interleukin 20 receptor subunit beta;interleukin-20 receptor subunit beta;interleukin 20 receptor beta |