| Description : |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Cynomolgus monkey |
| Form : |
Lyophilized |
| Molecular Mass : |
27.3 kDa |
| Protein Length : |
324 |
| AA Sequence : |
TMGLSNTLFVMAFLLSGAAPLKIQA YFNETADLPCQFANSQNRSLSELVV FWQNQENLVLNEVYLGKEKFDSVHS KYMGRTSFDPESWTLRLHNLQIKDK GLYQCIIHHKRPTGMIRIHQMNSEL SVLANFSQPEIVPISNITENMYINL TCSSIHGYPEPEKMSVLLRTKNSTI EYDGVMQKSQDNVTELYDVSISLSV SFPDVTSNMTIFCVLETDKTQLLSS PFSIELEDPQPPPDHIPWITAVLPT VIICVMAFCLILWKWKKKKQPRNSY KCGTNTMEREESEQTKKREKINVPE RSDEAQCVFKSLKTPSCDKSDTRF |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
