| Description : |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
| Source : |
HEK293 |
| Species : |
Cynomolgus monkey |
| Form : |
Lyophilized |
| Molecular Mass : |
19.2 kDa |
| Protein Length : |
254 |
| AA Sequence : |
MGNSCYNIVATLLLVLNFERTRSLQ DLCSNCPAGTFCDNNRSQICSPCPP NSFSSAGGQRTCDICRQCKGVFKTR KECSSTSNAECDCISGYHCLGAECS MCEQDCKQGQELTKKGCKDCCFGTF NDQKRGICRPWTNCSLDGKSVLVNG TKERDVVCGPSPADLSPGASSATPP APAREPGHSPQIIFFLALTSTVVLF LLFFLVLRFSVVKRSRKKLLYIFKQ PFMRPVQTTQEEDGCSCRFPEEEEG GCEL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
