Active Recombinant Dog CYP1A2 Protein
Cat.No. : | CYP1A2-119D |
Product Overview : | Recombinant dog CYP1A2 protein and human CYP-reductase without tag were coexpressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Cytochrome P450 1A2 (CYP1A2) is one of the CYP450 mixed-function oxidase system that is of clinical importance due to the large number of drug interactions associated with its induction and inhibition. |
Source : | E. coli |
Species : | Dog |
Bio-activity : | Cytochrome c Reductase Activity: 235 nmol/min/mg protein P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase]) Activity: 7-ethoxycoumarin O-deethylase Linear with time up to: 10 min(Determined at 1 µM substrate, using a P450 concentration of 2.5 pmol/ml) Linear with P450 up to: 10 pmol/ml(Determined at 1 µM substrate, using an incubation time of 5 min) Vmax: 1.3 pmol/min/pmol CYP Km: 1.1 μM |
Usage : | For laboratory (research) purposes only |
Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
Concentration : | P450 Concentration: 12.2 nmol/ml Protein Concentration: 10.0 mg/ml Specific P450 Content: 1220 pmol/mg protein |
Storage Buffer : | 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA |
Gene Name : | CYP1A2 cytochrome P450 family 1 subfamily A member 2 [ Canis lupus familiaris (dog) ] |
Official Symbol : | CYP1A2 |
Synonyms : | CYP1A2; cytochrome P450 family 1 subfamily A member 2; DAH2; CYPIA2; cytochrome P450 1A2; Cholesterol 25-hydroxylase; Cytochrome P450-D2; Cytochrome-P450-1A2; cytochrome P450, family 1, subfamily A, polypeptide 2; hydroperoxy icosatetraenoate dehydratase |
Gene ID : | 494010 |
mRNA Refseq : | NM_001008720 |
Protein Refseq : | NP_001008720 |
UniProt ID : | Q5R2U2 |
Products Types
◆ Recombinant Protein | ||
CYP1A2-132P | Active Recombinant Pig CYP1A2 Protein | +Inquiry |
Cyp1a2-2413M | Recombinant Mouse Cyp1a2 Protein, Myc/DDK-tagged | +Inquiry |
CYP1A2-2245H | Recombinant Human CYP1A2 Protein, GST-tagged | +Inquiry |
CYP1A2-1375R | Recombinant Rat CYP1A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP1A2-2796H | Recombinant Human CYP1A2 Protein, His-tagged, OVA Conjugated | +Inquiry |
◆ Lysates | ||
CYP1A2-432HCL | Recombinant Human CYP1A2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2126 | Cytochrome P450 1A2 Fluorometric Activity Assay Kit | +Inquiry |
Kit-2127 | Cytochrome P450 1A2 Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket