Active Recombinant Dog CYP2C21 Protein
Cat.No. : | CYP2C21-114D |
Product Overview : | Recombinant dog CYP2C21 protein without tag were coexpressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Showed testosterone hydrolase activity. |
Source : | E. coli |
Species : | Dog |
Bio-activity : | Cytochrome c Reductase Activity: 327 nmol/min/mg protein P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase]) Activity: Diclofenac 4’-hydroxylase Linear with time up to: 12 min(Determined at 30 µM substrate, using a P450 concentration of 100 pmol/ml) Linear with P450 up to: 125 pmol/ml(Determined at 30 µM substrate, using an incubation time of 5 min) Vmax: 1.7 pmol/min/pmol CYP Km: 57 μM |
Usage : | For laboratory (research) purposes only |
Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
Concentration : | P450 Concentration: 3.1 nmol/ml Protein Concentration: 16.2 mg/ml Specific P450 Content: 191 pmol/mg protein |
Storage Buffer : | 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA |
Gene Name : | CYP2C18 cytochrome P450 2C21 [ Canis lupus familiaris (dog) ] |
Official Symbol : | CYP2C21 |
Synonyms : | CYP2C21; cytochrome P450 2C21; CYP2C19; CYP2C21; CYPIIC21; cytochrome P450 2C21; Cytochrome-P450-2C21; cytochrome P450 DM1-1 |
Gene ID : | 415122 |
mRNA Refseq : | NM_001197044 |
Protein Refseq : | NP_001183973 |
UniProt ID : | P56594 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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