Active Recombinant Dog CYP2D15 Protein
| Cat.No. : | CYP2D15-116D |
| Product Overview : | Recombinant dog CYP2D15 protein without tag were coexpressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | High activity for the hydroxylation of bunitrolol and imipramine; low activity on debrisoquine. |
| Source : | E. coli |
| Species : | Dog |
| Bio-activity : | Cytochrome c Reductase Activity: 330 nmol/min/mg protein P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase]) Activity: Bufuralol 1’-hydroxylase Linear with time up to: 8 min(Determined at 3 µM substrate, using a P450 concentration of 5 pmol/ml) Linear with P450 up to: 15 pmol/ml(Determined at 3 µM substrate, using an incubation time of 5 min) Vmax: 5.4 pmol/min/pmol CYP Km: 6.2 μM |
| Usage : | For laboratory (research) purposes only |
| Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
| Concentration : | P450 Concentration: 5.2 nmol/ml Protein Concentration: 21.2 mg/ml Specific P450 Content: 245 pmol/mg protein |
| Storage Buffer : | 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA |
| Gene Name : | CYP2D15 cytochrome P450 2D [ Canis lupus familiaris (dog) ] |
| Official Symbol : | CYP2D15 |
| Synonyms : | CYP2D15; cytochrome P450 2D; CYP2D; CYPIID15; cytochrome P450 2D15; Cytochrome-P450-2D15; cytochrome P450 DUT2; cytochrome P450, family 2, subfamily D, polypeptide 15; monooxygenase |
| Gene ID : | 415120 |
| mRNA Refseq : | NM_001003333 |
| Protein Refseq : | NP_001003333 |
| UniProt ID : | Q29473 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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