| Species : |
Equine |
| Source : |
Yeast |
| Tag : |
Non |
| Description : |
Type I interferons (IFN alpha, IFN beta) belong to the helical cytokine superfamily, which includes growth hormones, interleukins, several colony-stimulating factors plus other regulatory molecules. All function as regulators of cellular activity by interacting with cell-surface receptors and activating various signaling pathways. IFN beta produces antiviral, antibacterial, and anticancer properties. RANKL (TNFSF11) has been shown to induce the production of IFN beta. |
| Form : |
Lyophilized without carrier protein. |
| Molecular Mass : |
Equine IFN beta 1 has a predicted molecular weight of 19.5 kDa. |
| AA Sequence : |
SYDVLRYQQR SSNLACQKLL GQLPGTPQYC LEDRMNFEVP EEIMQPPQFQ KEDAVLIIHE MLQQIFGILR RNFSSTGWNE TVIKTILVEL DGQMDDLETI LEEIMEEENF PRGDMTILHL KKYYLSILQY LKSKEYRSCA WTVVQVEILR NFSFLNRLTD YLRN |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Applications : |
The IFN beta protein can be used in cell culture, as a IFN beta ELISA Standard, and as a Western Blot Control. |
| Storage : |
Stable for up to twelve months from date of receipt at -20?C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20?C. Avoid repeated freeze/thaw cycles. |
| Reconstitution : |
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
