Recombinant Escherichia coli (strain UTI89/UPEC) clpP protein (ATP-dependent Clp protease proteolytic subunit), His/Myc-tagged
Cat.No. : | CLPP-1032E |
Product Overview : | Recombinant Escherichia coli (strain UTI89/UPEC) clpP protein (ATP-dependent Clp protease proteolytic subunit, 15-207aa), fused to 10×His-tag at N-terminus and Myc-tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | ClpP can simultaneously bind ClpX and ClpA to form a heteromeric complex. ClpP is a serine protease with a chymotrypsin-like activity that is a part of the ClpAP, ClpAPX and ClpXP protease complexes. Cleaves peptides in various proteins in a process that requires ATP hydrolysis. The protein has a chymotrypsin-like activity and plays a major role in the degradation of misfolded proteins. |
Source : | E.coli |
Species : | E.coli |
Tag : | His/Myc |
Form : | Tris-based buffer,50% glycerol. |
Molecular Mass : | 28.6 kDa |
Protein length : | 193 |
AA Sequence : | ALVPMVIEQTSRGERSFDIYSRLLK ERVIFLTGQVEDHMANLIVAQMLFL EAENPEKDIYLYINSPGGVITAGMS IYDTMQFIKPDVSTICMGQAASMGA FLLTAGAKGKRFCLPNSRVMIHQPL GGYQGQATDIEIHAREILKVKGRMN ELMALHTGQSLEQIERDTERDRFLS APEAVEYGLVDSILTHRN |
Purity : | Greater than 85% as determined by SDS-PAGE. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20/-80 centigrade. The shelf life of lyophilized form is 12 months at -20/-80 centigrade. Store working aliquots at 4 centigrade for up to one week. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Warning : | Repeated freezing and thawing is not recommended. |
Synonyms : | ECK0431; lopP |
UniProt ID : | Q1RF98 |
Synonyms : | ECK0431; lopP |
UniProt ID : | Q1RF98 |
Products Types
◆ Recombinant Protein | ||
CLPP-1971C | Recombinant Clostridium Botulinum CLPP Protein (1-194 aa), His-SUMO-tagged | +Inquiry |
Clpp-2197M | Recombinant Mouse Clpp Protein, Myc/DDK-tagged | +Inquiry |
CLPP-1512H | Recombinant Human CLPP Protein, GST-tagged | +Inquiry |
CLPP-1766M | Recombinant Mouse CLPP Protein, His (Fc)-Avi-tagged | +Inquiry |
CLPP-2847Z | Recombinant Zebrafish CLPP | +Inquiry |
◆ Lysates | ||
CLPP-7434HCL | Recombinant Human CLPP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionTargeting CLPP therapeutically could offer potential in diseases related to mitochondrial dysfunction and aging.
CLPP activity is tightly regulated to ensure balanced protein turnover in mitochondria.
Dysregulation of CLPP is linked to various diseases, including mitochondrial disorders.
It helps in degrading misfolded or damaged proteins, maintaining mitochondrial function.
Proper functioning of CLPP is vital for mitochondrial health and energy production.
CLPP levels and activity are associated with aging, influencing cellular senescence and longevity.
CLPP plays a crucial role in mitochondrial protein degradation and quality control.
Customer Reviews (3)
Write a reviewVery high purity level.
Worked excellently in experiments.
Product was well packaged.
Ask a Question for All clpP Products
Required fields are marked with *
My Review for All clpP Products
Required fields are marked with *
Inquiry Basket