Recombinant Full Length Human ABHD6 Protein, C-Flag-tagged

• Cat.No.: ABHD6-475HFL
• Product Overview: Recombinant Full Length Human ABHD6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity). Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38.2 kDa
• AA Sequence: MDLDVVNMFVIAGGTLAIPILAFVA SFLLWPSALIRIYYWYWRRTLGMQV RYVHHEDYQFCYSFRGRPGH KPSILMLHGFSAHKDMWLSVVKFLP KNLHLVCVDMPGHEGTTRSSLDDLS IDGQVKRIHQFVECLKLNKK PFHLVGTSMGGQVAGVYAAYYPSDV SSLCLVCPAGLQYSTDNQFVQRLKE LQGSAAVEKIPLIPSTPEEM SEMLQLCSYVRFKVPQQILQGLVDV RIPHNNFYRKLFLEIVSEKSRYSLH QNMDKIKVPTQIIWGKQDQV
  LDVSGADMLAKSIANCQVELLENCG HSVVMERPRKTAKLIIDFLASVHNT DNNKKLDTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: ABHD6 abhydrolase domain containing 6, acylglycerol lipase [ Homo sapiens (human) ]
• Official Symbol: ABHD6
• Synonyms: abhydrolase domain containing 6; lipase protein
• Gene ID: 57406
• mRNA Refseq: NM_020676.7
• Protein Refseq: NP_065727.4
• MIM: 616966
• UniProt ID: Q9BV23