Recombinant Full Length Human ACTR3 Protein, C-Flag-tagged

• Cat.No.: ACTR3-1248HFL
• Product Overview: Recombinant Full Length Human ACTR3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.2 kDa
• AA Sequence: MAGRLPACVVDCGTGYTKLGYAGNT EPQFIIPSCIAIKESAKVGDQAQRR VMKGVDDLDFFIGDEAIEKP TYATKWPIRHGIVEDWDLMERFMEQ VIFKYLRAEPEDHYFLLTEPPLNTP ENREYTAEIMFESFNVPGLY IAVQAVLALAASWTSRQVGERTLTG TVIDSGDGVTHVIPVAEGYVIGSCI KHIPIAGRDITYFIQQLLRD REVGIPPEQSLETAKAVKERYSYVC PDLVKEFNKYDTDGSKWIKQYTGIN AISKKEFSIDVGYERFLGPE IFFHPEFANPDFTQPISEVVDEVIQ NCPIDVRRPLYKNIVLSGGSTMFRD FGRRLQRDLKRTVDARLKLS EELSGGRLKPKPIDVQVITHHMQRY AVWFGGSMLASTPEFYQVCHTKKDY EEIGPSICRHNPVFGVMSTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: ACTR3 actin related protein 3 [ Homo sapiens (human) ]
• Official Symbol: ACTR3
• Synonyms: ARP3
• Gene ID: 10096
• mRNA Refseq: NM_005721.5
• Protein Refseq: NP_005712.1
• MIM: 604222
• UniProt ID: P61158